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It would seal the skin but also provide a more durable covering that would protect while the skin healed.
If there is a way to cushion the hand/wrist or the chest that might be helpful as well. Prevention is better than trying to provide "a band-aid cure"
An extra lap blanket maybe or "lambs wool" protector might help. Kinda like that "Sherpa" material
A bit off topic but when I had to start giving my Husband Morphine (very small doses) I was actually able to move his hand and arm out of the contracted position for the first time in a while. And he was able to maintain a more relaxed position for a while after medication. For the fact that he was able to relax for the first time in a very long time I was thankful for the Morphine.
As far as moisturizer I would "slather" him after shower or bed bath with a lotion that I would combine with a heavier barrier cream with zinc in it. The one with zinc was very heavy and the lotion seemed not to last long by mixing the 2 I had a creamy lotion that would last most of the day. I would do hands and feet again during the day.
We did dressing changes 2-3xs a day---and sadly, I was never able to keep up with the new ones, nor did the old ones ever heal. It was a losing battle, but I kept him comfortable, which is all I could hope for.
1 - Only use a soap that is pH balanced. If your patient is older, try a cleansing lotion - one with moisturizers - rather than straight soap which can strip skin oils.
2 - Make sure to dry his/her skin well before applying lotion.
3 - I like lotions that contain jojoba or shea, but baby lotion can work well too. Use them after cleansing the skin and a couple of times during the day is skin is dry.
4 - If the person tends to get sweaty, crumbly skin, then moisture is a problem. Try to get the "sweaty areas" opened up a couple of times a day. Use passive range of motion exercises. Sometimes it helps to put a clean dry washrag into areas where skin meets skin.
5 - Sounds like part of the problem is also "friction." Try to reduce friction by covering the areas that rub with clothing. The wrist might do better with a wrist band, something like a smooth knit sock, that keeps the skin on the wrist from rubbing against anything.
I use Butt Paste on his butt and he's never had a bed sore.
But my Dad's skin is Super thin so if he had an area like your talking about, I would let him wear 100% Cotton long sleeve T Shirts to help protect his skin.
Moisturizing: Sad but true, I use a lot of Asian beauty products and also use them on my gardening scratches and abrasions. Decided to try them on Mom to keep the 'new' skin supple. I did a moisturizing serum (or one of my heavier overnight 'face pack' lotions) as they seal in moisture like nobody's business. They are geared to be gentle. Not shilling for anyone, but this is what I used if you're interested-These are supposed to be tapped in lightly and a very little goes a long way. The Japanese products tend to be very minimalistic in terms of additives.
https://smile.amazon.com/Rohto-Gokujyn-Hyaluronic-Lotion-170ml/dp/B07DMZ76GF/ref=sr_1_18?crid=1OVRJO082TKY1&dchild=1&keywords=hada+labo+hyaluronic+acid&qid=1625150693&sprefix=had%2Caps%2C180&sr=8-18
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