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A cpap machine (which is not oxygen) made a huge difference in my life. But I clearly had sleep apnea, as determined by standard tests. Someone who had similar symptoms to mine but who did not have sleep apnea would not benefit from wear that cumbersome mask. Good solutions only work when they are applied to the right problems.
I really really hope your Mom has future success with the oxygen. Please keep up updated!
A person on oxygen could have Vascular dementia or Dementia with Lewy Bodies or Alzheimer's or any other kind of dementia. The oxygen would not cure those disorders. But if the cognitive decline were due to insufficient oxygen reaching the brain (and I know nothing about that) then, well, I guess getting enough oxygen would be the cure. I certainly hope it is in your mother's case.
I wonder if Mom had had a thorough workup by a geriatrician or a dementia specialist when she first began to decline if this would have been discovered then?
We are going to be eagerly awaiting the next installment!