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I have seen progression occur in various ways. My LO, who has Vascular dementia, has had her stepped down progression occur pretty quickly. She went from walking with a care to a walker in a few days. Then, she went to a wheelchair in a few days. More recently, she stopped being able to sit up very well, within a couple of days. All things have been checked, like UTI (treated and cleared), brain scan, and medication adjustment, but, it persists. We are now wondering if she might also have Alzheimers. It's not uncommon to have both, but, it's my understanding that AD is more of a gradual change.
Is there a geriatric psychiatrist or other doctor who is familiar with dementia who can listen to your description of what is going on? A seasoned practitioner will understand what is up and be able to prescribe the right meds to ease her in the evenings.
1) Reaction to a medication, including inadvertently stopping one abruptly, taking too much, side effects kicking in ...
2) An illness. UTIs are notorious in this regard, but any infection can cause this, as can a cough, constipation ... anything not right with the body.
3) Progression of the dementia pathology itself.
Best wished to you.
There is something going on.
Did they do a urine culture (takes at least 24 hours) or just a "dipstick"?